Understanding Acute Myeloid Leukemia (AML): Classification, Subtypes, and Hematological Features
Acute Myeloid Leukemia (AML) Acute Myeloid Leukemia (AML) is a rapidly progressing cancer that affects the blood and bone marrow, characterized by the rapid growth of abnormal myeloid cells. OR Acute Myeloid Leukemia (AML) is a type of blood cancer. In children, it occurs in about 2 to 3 out of every 100,000 children per year.In older adults, particularly those over 60 years old, the incidence rises significantly to around 15 cases per 100,000 people per year. WHO Classification (Newer): Incorporates and interrelates morphology (cell appearance), cytogenetics (chromosomal abnormalities), molecular genetics (genetic mutations), and immunologic markers (cell surface proteins). Allows for a more comprehensive understanding of leukemia subtypes by considering multiple factors. Defines acute leukemia as having 20% or more blasts (immature cells) in the blood and bone marrow. FAB Classification (Older): Primarily based on morphological features observed under the micro...